CHIRALITY IN NATURAL AND APPLIED SCIENCES

• Dr J W Lough - Reader in Pharmaceutical Analysis, University of Sunderland, UK
• Professor I Wainer - Senior Investigator in the Bioanalytical and Drug Discovery Unit of the National Institute on Aging, National Institutes of Health, Baltimore, USA

An understanding of chirality is central to the study and application of the molecular sciences. Chirality in Natural and Applied Science provides a highly practical overview of the chemical significance of chirality and is particularly relevant for pharmaceutical, natural product, organic and analytical chemists, biochemists and molecular biologists.

The book describes the current understanding of all issues relating to chirality, and appraises its impact on much of modern molecular science. It covers the natural occurrence of chirality on a variety of scales, and applications in research and industry. By bringing together the experience of a number of contributors who have played an influential role on the direction of research in this area, the text is well placed to explain the most important insights, developments and applications that have taken place.

Chirality will remain a central part of the understanding of all molecular scientists, and there is little doubt that its importance will increase. This book will ensure the reader has a thorough understanding of chirality, its importance and its application.

• Authoritative review ensures the reader has a thorough understanding of chirality, its importance and its application
• Ideal for graduates or as a reference for experienced scientists, the text explains in detail the insights, developments and applications that have driven our understanding of chirality
• Internationally respected editors and authors deliver a book that will be essential reading for all pharmaceutical, natural product, organic and analytical chemists, biochemists and molecular biologists

Introduction;
Pasteur on molecular handedness - and the sequel;
The origin of biomolecular chirality;
Chirality at the sub-molecular level: true and false chirality;
The molecular basis of chiral recognition;
Chirality in drug design and development;
Chirality in medicinal chemistry;
Separation of chiral compounds - from crystallisation to chromatography;
Electronic circular dichroism - fundamentals, methods and applications;
Chirality in the natural world: chemical communications;
Chirality in the natural world: odours and tastes;
Chirality in the natural world: life through the looking glass;
Concluding remarks - chirality, chemistry, the future;
References
 

100 illustrations, 336 pages, Hardback, 0632054352, Price £89.50, Due May 2002
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