CHIRALITY-2001 (ISCD 13)

Thirteenth annual Symposium on Chirality
Chairman: Professor Dan Armstrong, Iowa State University
Orlando, Florida (Disney's Contemporary Resort)
July 15-18, 2001

Scope
Call for Posters
Abstract Submission form
Best Poster Competition
Schedule
Short Courses
Exposition
Vendor Seminars
Preliminary Scientific Program
Meeting Registration
Hotel/Travel
For Information, Contact
Chirality Medal Recipients
Committee

SCOPE(Sunday - Wednesday)

Chirality-2001 (ISCD 13) will be held in Orlando, Florida, USA, from Sunday, July 15 through Wednesday, July 18, 2001. Short courses will be offered all day Sunday, followed by the Opening of the meeting with the presentation of the Chirality Medal Award and lecture from this year's Chirality Medal Award recipient, Yoshio Okamoto from the University of Nagoya in Japan, followed by a welcome reception at the Contemporary Resort's Marina in Walt Disney World. This symposium series, which alternates between the United States, Europe and Japan, is the premier meeting for the presentation and discussion of recent scientific and technological advances related to all aspects of molecular chirality. The special topics of this year's meeting will be "Industrial, Bioanalytical, and Biological Aspects of Chirality." Symposium highlights:

  • FDA talk on Chiral Analysis
  • Special Discussion Session on Regulatory Issues
  • New Session on Mass Spec Evaluation of Enantiomers and e.e. Determinations
  • New Session on Biological Aspects of Chirality
  • Latest Advances in Chiral Separations
  • Latest Advances in Asymmetric Synthesis
  • Latest Advances in Chiroptical Spectroscopy
  • Latest Advances in Pharmacology and Regulatory Affairs (including the latest work on the biotransformation of thalidomide)
  • Three Short Courses on Sunday
  • Chirality Medal Award & Lecture Presentation on Sunday
  • Poster Competition with cash prizes
  • All the entertainment, recreation, etc. opportunities
Advanced techniques of enantioselective analysis and synthesis have spurred advances in the pharmaceutical and biological sciences. Today, studies can be done routinely that would have been difficult and time-consuming a decade ago. Quality control of chiral products and e.e. determinations now are done routinely and more accurately with one or more of a plethora of analytical separation methods. Chiroptical methods have advanced to the point that they are widely useful and sufficiently sensitive for a variety of analytical determinations. Process scale enantiomeric separations, large-scale asymmetric syntheses, and combinations of the two are making a significant impact on many industries. Most of these developments and advances ultimately relate back to biology at some point (although there may be a strict theoretical focus in some cases). This symposium will provide the largest and most thorough coverage of all aspects and advances related to chirality, and its impact on science and technology.

CALL FOR POSTERS — Taking into account that exciting developments are occurring at a rapid pace, we encourage you and your colleagues to submit a last minute contribution covering all aspects of molecular chirality, chiral recognition and discrimination. You are encouraged to submit abstracts electronically through our web site at www.chiral.com. If you do not have access to the web, you may submit by e-mail to janetbarr@aol.com. If sending as an attached file, send in IBM Word Format and cut-and-paste the abstract into the e-mail. Indicate name of meeting and presenting author; do not include graphics or figures. The deadline to submit is JUNE 15, 2001. The size of each poster board is 4 feet high by 8 feet wide.

POSTER COMPETITION(Cash Award for Winning Posters) —Poster presentations are a vitally important component of the Chirality Symposia. In order to acknowledge their contribution to the high standards and in-depth communications amongst practitioners, cash will be offered to the best posters at Chirality-2001. Posters will be evaluated on the basis of scientific content, clarity of presentation, and layout. The deadline to submit abstracts is JUNE 15 (the competition has been made possible by BioTools).

VENDOR SEMINARS — (Monday-Tuesday-Wednesday)
As a result of strong encouragement from participants who attended the last Symposium, special scientific seminars on different techniques or types of applications will augment the program. Symposium registrants who wish to participate in the free seminars must pre-register on-site at the booth of the seminar sponsor located in the Exhibit area. A complimentary continental breakfast will be included for all morning seminars; a complimentary small lunch will be included for all noontime seminars.

EXHIBIT — An integral part of the scientific program is the exhibit. The program is structured to ensure participants have ample opportunities to meet commercial suppliers who will feature state-of-the-art scientific services, equipment, literature and software in the closely integrated lecture and poster/trade display areas. List of exhibitors: Advanced Separation Technologies, Beckman Coulter, BioTools, Chiral Technologies, Eka Chemicals, Iris Technologies, Jasco, NovaSep, PDR-Chiral, Regis Technologies, RS Tech,  UPT, ModCol, Kingchem,

PROCEEDINGS — Symposium proceedings will be published in the journal,
Chirality. Contributors to Chirality who would like instructions for
manuscript preparation should visit: http://www.interscience.wiley.com/jpages/0899-0042/

SOCIAL PROGRAM

WELCOME RECEPTION (Sunday)
After a day of short courses, the meeting will Open with the presentation of the Chirality Medal Award followed by a lecture by this year's Chirality Medal Award recipient, Prof. Yoshio Okamoto, University of Nagoya in Japan. After the presentation, a Welcome Reception will be hosted by Chiral Technologies at the Contemporary Resort's Marina (included in registration fee).

Evening at Leisure (Monday)

BANQUET DINNER & DESSERT RECEPTION AT WALT DISNEY WORLD'S EPCOT® (Tuesday)
Travel with us from the Contemporary Resort in the Magic Kingdom to Walt Disney World's Epcot® where we will dine in the American Adventure Rotunda. After dinner, Regis Technologies will host a Dessert Reception beside the World Showcase Lagoon offering a spectacular view to enjoy Epcots® IllumiNations—a spectacular rhapsody of lasers, lights, fountains, music and fireworks! $50 per person includes bus, admission into Epcot®, dinner, dessert and show. Reserve early as seating is limited; see Meeting Registration Form.

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CALL FOR POSTERS 

Abstract Submission form -- Posters Abstracts Due June 15, 2001

Submissions of abstracts covering all aspects of molecular chirality, chiral recognition and discrimination are welcome from scientists and practitionersworld-wide. The broad spectrum of lecture and poster presentations will create an interdisciplinary forum highlighting the following scientificthemes. The deadline to submit abstracts for lecture consideration has passsed. We are now encouraging you to submit your abstract for poster consideration by JUNE 15, 2001. Please submit abstracts electronically by e-mail to janetbarr@aol.com. If sending as an attached file, send in IBM Word format and cut-and-paste the abstract into the e-mail. Do not include graphics or figures. Be sure to provide information outlined on the Abstract Submission Form

· New methods for enantiopurity analysis and assignment of absolute
configuration
· Recent developments in biological enantioselectivity
· Pharmaceutical and metabolite analysis
· Enantiomeric separations by capillary electrochromatography
· Fundamental aspects of chirality and enantiomer discrimination including
history, nomenclature and theoretical studies
· New developments in asymmetric synthesis
· New manufacturing routes to enantiopure materials
· Process development for enantiopure materials
· Resolution techniques involving crystallization
· Large scale chromatographic separation of enantiomers
· Recent developments in chiroptical spectroscopy
· Studies relating to enantioselective metabolism and pharmacodynamics

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Schedule

 
 		 September 2000 Call for papers 
 
 		 November 12, 2000  Abstract Deadline for Lectures. 
POSTER Abstract Deadline JUNE 15, 2001
 
 		 March 2001  Final Circular. Preliminary Program, Registration and Housing Information
 
 		 July 15-18, 2001  Symposium, Courses and Manuscripts Due
Sunday, July 15
Monday, July 16
Tuesday, July 17
Wednesday, July 18

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Short Courses (Sunday)
Short courses are available the Sunday preceding the meeting at a cost of $270. See Meeting Registration Form to pre-register.

Chiral Organoboranes for Asymmetric Syntheses
Will cover basic and large-scale industrial synthesis of chiral compounds. Short course participants should have good background knowledge of basic organic chemistry. Instructor: P.V. Ramachandran

High Efficiency Enantioselective Separations
Will cover all classes of chiral selectors for HPLC as well as CE, SFC, and GC. Some history, nomenclature, use, and mechanistic aspects will be included. It is assumed that all short course participants have had basic organic chemistry and are familiar with routine HPLC. Instructors: T.J. Ward, D.W. Armstrong

Chiroptical Spectroscopy and NMR for Determining e.e.s and Absolute Configurations
It is assumed that all short course participants have had basic organic chemistry and have some knowledge of basic spectroscopy. Instructors: N. Berova, L. Di Bari
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EXPOSITION

A integral part of the scientific program is the exhibit. The program is structured to ensure participants have ample opportunities to meet commercial suppliers who will feature state-of-the-art scientific services, equipment, literature and software in the closely integrated lecture and poster/trade display areas. Vendor seminars will also be presented during the program (see section, VENDOR SEMINARS). To reserve booth space, exhibitors should contact the Symposium Manager, Ms. Janet Cunningham, at janetbarr@aol.com  (301-668-6001).

Corporate Sponsors

BioTools • Chiral Technologies • Regis Technologies

Final List of Exhibitors

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VENDOR SEMINARS

As a result of strong encouragement from participants who attended the last Symposium, special scientific seminars on different techniques or types of applications will augment the program. Symposium registrants who wish to participate in the free seminars must pre-register on-site at the booth of the seminar sponsor located in the Exhibit area. A complimentary continental breakfast will be included for all morning seminars; a complimentary small lunch will be included for all noontime seminars.

For Vendors Only: Please select your Time Slot Preferences (indicate 1st and 2nd choices). Must be an exhibitor to present a vendor seminar. Contact the Symposium Manager for details regarding cost and time slot preference, phone 301-898-3772 or janetbarr@aol.com

  • Monday Seminar 12:00 - 1:00 pm ...... Unambiguous Determination of Absolute Configuration (and Conformations) of Chiral Molecules in Solution using VCD -- No Need for Crystals or X-rays, sponsored by BioTools
  • Monday Seminar 12:00 - 1:00 pm ...... New Trends in Chiral Separations, sponsored by NovaSep
  • Tuesday Seminar 7:00 - 8:00 am ....... Chiral Detection in SFC and HPLC, sponsored by Jasco
  • Tuesday Seminar 7:00 - 8:00 am ....... Bulk Chiral Stationary Phase in Preparative Simulated Moving Bed Chromatography, by Chiral Technologies
  • Tuesday Seminar 12:00 - 1:00 pm ...... Chiral Separations. Part A: LC/MS/MS..Screening by Column Coupling. Part B: New Methodology for Preparative Processing on Macrocyclic Glycopeptides, sponsored by Advanced Separation Technologies
  • Tuesday Seminar 12:00 - 1:00 pm ...... Properties and Capabilities of the New DACH-DNB Chiral Stationary Phase/Chiral HPLC Method Development Question and Answer Session, sponsored by Regis Technologies
  • Wednesday Seminar 7:00 - 8:00 am ... Chiral Separations by SFC, sponsored by Berger Instruments
  • Wednesday Seminar 7:00 - 8:00 am ...
  • Wednesday Seminar 12:00 - 1:00 pm .. Optimizing the Development and Production of Enantiomerically Pure Pharmaceuticals-- Techniques and Systems Utilizing "Advanced Laser Polarimeter" Technology, sponsored by PDR-Chiral
  • Wednesday Seminar 12:00 - 1:00 pm ... VARICOL: A New, Non-SMB, Multi-column Chromatographic Process for the Production of Pure Enantiomers, sponsored by NovaSep
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MEETING REGISTRATION

Meeting RegistrationFees are printed on the attached Meeting Registration Form. To be eligible for the student reduced rate of $100, send verification of your current full-time graduate or undergraduate, not post-doctoral, status at an academic institution by providing both a copy of your Student I.D. and letter signed by your department chairman on University stationery.

To Register Meeting registrants should complete and return the Meeting Registration Form in the booklet to: Ms. Janet Cunningham, Chirality-2001 Symposium Manager, P.O. Box 279, Walkersville, Maryland 21793 USA, or fax the form to 301-898-5596. Pre-registrations will be accepted until June 28, 2001. After June 28, you must register on-site at the Symposium. Each applicant must complete a separate registration form. Make copies of the Meeting Registration Form as needed.

PaymentChecks must be made payable in U.S. dollars and be drawn on a U.S. bank. MasterCard and Visa credit card payments will be accepted. Bank transfers of U.S. dollars must be received prior to the meeting—and be sent to: Chirality-2001, Farmers & Mechanics National Bank, 110 Thomas Johnson Drive, Frederick, Maryland 21702 USA (routing # 055000262; account # 2528150). Attach proof of bank transfer with Meeting Registration Form.

CancellationA non-refundable fee of $100 will apply to all cancellations received in writing before May 25, 2001, and will be processed after the meeting. No refunds will be made after that date. Contact the Symposium Manager.

HOTEL / TRAVEL


Meeting SiteDisney’s Contemporary Resort is located the heart of Walt Disney’s Magic Kingdom Theme Park at 4600 N. World Drive, Lake Buena Vista, Florida 32830, USA (ph 407-824-1000; fax 407-824-3539).

HotelIt will be wise to make your hotel reservation as early as possible—the hotel will definitely sell out of rooms during this time of year. To obtain the discounted room rate of $165 per night (single or double), you must make your reservation well before May 30, 2001. Reservations must be confirmed and guaranteed with one night's deposit plus 11% tax. Note, you must cancel at least five days prior to arrival to receive a refund. Check-in time is 3:00 pm and check-out time is 11:00 am. Make your reservation by calling Disney’s Contemporary Resort at 407-824-3869 and be sure to cite the name of the meeting—Chirality-2001 (fax 407-824-3738). Make sure you request and receive written confirmation.

TravelDisney’s Contemporary Resort is located in Disney's Magic Kingdom Theme Park in Lake Buena Vista, Florida ~25 miles from Orlando International Airport. Taxi fare from Orlando International Airport is ~ $35.00-40.00.

Airport ShuttleMears Airport Shuttle (407-423-5566). From Orlando International Airport to Disney’s Contemporary Resort: Tickets can be purchased at ticket counters located on Level 2 (baggage claim) and Level 1 (shuttle van pick-ups)—flights arrive on Level 3--or from the driver at the time of boarding the shuttle. For return to the airport: Return reservations are required at least one day prior to departure. Allow a minimum of two hours before your flight time. There are shuttle boards at the entrance of every Walt Disney World Resort hotel. Shuttles leave every 25-30 minutes, 24 hours a day. Cost: adults age 12 and over, ~$15.00 one-way/~$27.00 round-trip; children age 4-11, ~$11.00 one-way/~$19.00 round-trip; children 3 and under, free.

ParkingDisney’s Contemporary Resort offers general parking at no charge for hotel guests. Valet parking is free, but they do accept tips.

Health ClubDisney’s Contemporary Resort offers the use of the exercise room located on the 3rd floor of the main building at a cost of $12 per day or $22 for length of stay.

Theme Park Tickets Specially priced convention tickets for Walt Disney World® Theme Parks and attractions may be purchased on-site at the front desk of the Contemporary Resort, or through their web site at www.conventionplus.com/Contemporary

Visitor InfoContact Orlando/Orange County Convention & Visitors Bureau, ph 407-248-5782 or visit the web site at www.go2orlando.com/cvb

ClimateMid-July in Orlando is tropical with temperatures ranging from a high of 95ºF (35ºC) to a low of 80ºF (26ºC).

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CONTACT

Ms. Janet Cunningham
Chirality-2001 Symposium/Exhibit Manager
Barr Enterprises
PO Box 279
Walkersville, MD 21793 USA

Phone: 301-668-6001
Fax: 301-668-4312
Email: JanetBarr@aol.com
Website: www.chiral.com/ISCD/

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The Chirality Medal has been awarded to the following scientists 

               1991 E. Gil-Av (Israel) and J. Jacques (France)
               1992 V. Prelog (Switzerland)
               1993 K. Mislow (USA)
               1994 W. Pirkle (USA)
               1995 K. Nakanishi (USA)
               1996 E. L. Eliel (USA)
               1997 R. Noyori (Japan)
               1998 H. Kagan (France)
               1999 V. Davankov (Russia)
               2000 B. Sharpless (USA)
               2001 Y. Okamoto (Japan)

International Scientific Committee of the ISCD Series 

Daniel W. Armstrong (Ames, IA, USA)
Nina Berova (New York, NY, USA)
John Caldwell (London, UK)
Vadim A. Davankov (Moscow, Russia)
Ernest L. Eliel (Chapel Hill, NC, USA)
Anthony F. Fell (Bradford, UK)
Wolfgang Lindner (Vienna, Austria)
Domenico Misiti (Roma, Italy)
Yoshio Okamoto (Nagoya, Japan)
William H. Pirkle (Urbana, IL, USA)
Kazuhiko Saigo (Tokyo, Japan)
Volker Schurig (Tubingen, Germany)
Organizing Committee
Nina Berova, Columbia University
P.V. Ramachandran, Purdue University
George Reid, Pfizer
Kimber Rundlett, Pfizer
Rekha D. Shah, R.W. Johnson PRI
Apryll Stalcup, University of Cincinnati
Timothy Ward, Millsaps College
Christopher Welch, Merck & Co., Inc.
Symposia in the Series of Intl. Symposia on Chirality

1st ISCD 1988 ...... Paris, France
2nd ISCD 1991...... Rome, Italy ..................D. Misiti
3rd ISCD 1992 ..... Tübingen, Germany .......V. Schurig
4th ISCD 1993 ..... Montreal, Canada ...........I. Wainer
5th ISCD 1994 ..... Stockholm, Sweden .......U. Hacksell
6th ISCD 1995 ..... St. Louis, MO, USA .......D. Armstrong
7th ISCD 1995 ..... Jerusalem, Israel ............I. Agranat
8th ISCD 1996 ..... Edinburgh, UK ..............W. Lough
9th ISCD 1997 ..... Nagoya, Japan ..............Y. Okamoto
10th ISCD 1998 ... Vienna, Austria .............W. Lindner
11th ISCD 1999 ... Chicago, IL, USA ...........W. Pirkle & C. Welch
12th ISCD 2000 ... Chamonix, France .........A. Collet
13th ISCD 2001 ... Orlando, FL, USA ..........D. Armstrong
14th ISCD 2002 ... Hamburg, Germany .......W. Koenig

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Sunday, July 15, 2001

8am Registration Open for Short Courses

Short Courses

8:30am-4:00pm Chiral Organoboranes for Asymmetric Syntheses

  • Will cover basic and large-scale industrial synthesis of chiral compounds. Short course participants should have good background knowledge of basic organic chemistry. Instructor: P.V. Ramachandran
    •  8:30am-4:00pm High Efficiency Enantioselective Separations
  • Will cover all classes of chiral selectors for HPLC as well as CE, SFC, and GC. Some history, nomenclature, use, and mechanistic aspects will be included. It is assumed that all short course participants have had basic organic chemistry and are familiar with routine HPLC. Instructors: T.J. Ward, D.W. Armstrong
    •  8:30am-4:00pm Chiroptical Spectroscopy and NMR for Determining ee's and Absolute Configurations
    • It is assumed that all short course participants have had basic organic chemistry and have some knowledge of basic spectroscopy. Instructors: N. Berova, L. Di Bari
    Opening of Program and Chirality Award Lecture

    3:00-8:00pm Symposium Registration Open

    5:30pm WELCOME / CHIRALITY AWARD COMMENTS

    5:45pm CHIRALITY MEDAL AWARD LECTURE — Polysaccharide Derivatives as Potential Chiral Stationary Phases for HPLC—Yoshio Okamoto, Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, JAPAN

    6:45-8:45 WELCOME RECEPTION — Hosted by Chiral Technologies
    Contemporary Resort (included in registration fee)

    Monday, July 16, 2001

    Session 1. Biological Chirality

    8:30am Substrate Recognition by Mammalian Peptide Transporters: Enantioselective Promiscuity—H. Daniel, Technical University of Munich, Freising-Weihenstephan, GERMANY

    9:00am Symmetry-Breaking in Animals: Phylogenetic Patterns of Asymmetry Variation and Their Evolutionary Significance—A.R. Palmer, University of Alberta, Alberta, CANADA

    9:30am Cave Bear Dentine Amino Acids Chirality: The Key for Iberian Hominid Bearing Hominid Beds Dating—T. de Torres, Madrid School of Mines, Madrid, SPAIN

    10:00am Break in Exhibit Hall / Exhibits Open

    10:30am Genetic Control of Left-Right Asymmetry in Embryos, Heart and Viscera—M. Brueckner, Yale University, New Haven, CT, USA

    11:00am Enantioselective Gas Chromatography in Stereochemical Studies of Natural Compounds—W.A. Koenig, Universitaet Hamburg, Hamburg, GERMANY

    11:30am Session Ends

    12:00-1:00pmVENDOR SEMINAR on Unambiguous Determination of Absolute Configuration (and Conformations) of Chiral Molecules in Solution Using VCD–No Need for Crystals or X-rays, sponsored by BioTools (must pre-register at BioTools’ booth/complimentary lunch provided)

    12:00-1:00pm VENDOR SEMINAR on New Trends in Chiral Separations, sponsored by NovaSep (must pre-register at NovaSep’s booth/complimentary lunch provided)

    1:15-2:45pm POSTER SESSION in Exhibit Hall

    Session 2. Mass Spectrometry in Enantiomeric Analysis

    2:45pm Chiral Analysis by Mass Spectrometry—R.G. Cooks, W.A. Tao, Purdue University, West Lafayette, IN, USA

    3:15pm The Determination of Enantiomeric Excess in Peptides and
    Unusual Amino Acids by Mass Spectrometry—C. Lebrilla, University of
    California, Davis, CA, USA

    3:45pm A New Method for Determining the Enantiomeric Excess of Chiral Alcohols Using 2-Methoxy-2-(1-Naphthyl)Propionic Acid—N. Harada, H. Taji, M. Watanabe, Tohoku University, Sendai, JAPAN

    4:05pm Break in Exhibit Hall

    4:30pm The Use of Atmospheric Pressure Ionization Mass Spectrometry in Enantioselective Liquid Chromatography—R. Bakhtiar, Novartis Institute for Biomedical Research, East Hanover, NJ, USA

    5:05pm Rapid Evaluation of Chiral Stationary Phase Libraries by Mass Spec Using Isotopically Labeled Pseudoenantiomers—C.J. Welch, Merck & Company, Rahway, NJ, USA

    5:30pm Quinine, Quinidine and Their Tert-Butyl Carbomylated Derivatives as New Chiral Selectors in the Potentiometric, Enantioselective Membrane Electrodes Design. Their Application for the Assay of S and R Enantiomers of Dinitrobenzene Leucine—R.-I. Stefan1, W. Lindner2, N.M. Maier2, J.F. van Staden1, 1University of Pretoria, Pretoria, SOUTH AFRICA; 2University of Vienna, Vienna, AUSTRIA

    5:50pm Session Ends (evening at leisure)

    Tuesday, July 17, 2001

    7:30-8:30am VENDOR SEMINAR on Chiral Detection in SFC and HPLC, sponsored by Jasco (must pre-register at Jasco’s booth/complimentary continental breakfast provided)

    7:30-8:30am VENDOR SEMINAR on Bulk Chiral Stationary Phase in Preparative Simulated Moving Bed Chromatography, sponsored by Chiral Technologies (must pre-register at Chiral Technologies’ booth/complimentary continental breakfast provided)

    Session 3. Enantiomeric Separations I

    8:50am Enantiomer Separations Using Antibody-Based Stationary Phases—O. Hofstetter, H. Hofstetter, Northern Illinois Univ., DeKalb, IL, USA

    9:20am Native and Single Isomer Derivatized Cyclodextrins as Chiral Receptors for Chiral and Achiral Separations and Sensing—M. Sepaniak, G. Devault, J. Scheaper, C. Tipple, N. Lavrik, University of Tennessee, Knoxville, TN, USA

    9:40am Investigation of the Chiral Recognition Mechanism of Teicoplanin Bonded Phases Using Copper Complexation and Deuterium Isotope Exchange—A. Berthod, Universite de Lyon I, Villeurbanne, FRANCE

    10:00am Break in Exhibit Hall / Exhibits Open

    10:30am Peptide Enantiomers, Trials to Separate Them Using LC, CEC, and CE Techniques—W. Lindner, M. Laemmerhofer, C. Cerwenka, University of Vienna, Vienna, AUSTRIA

    11:00am Chemically Modified Chiral Stationary Phase on Monolithic Silica Column for Micro-HPLC and CEC—Z. Chen, T. Hobo, Tokyo Metropolitan University, Tokyo, JAPAN

    11:20am Screening of Combinatorial Libraries for Chiral Selectors—T. Li, Vanderbilt University, Nashville, TN, USA

    11:40am Session Ends

    12:00-1:00pm VENDOR SEMINAR on Chiral Separations. Part A: LC/MS/MS: Screening by Column Coupling. Part B: New Methodology for Preparative Processing on Macrocyclic Glycopeptides, sponsored by Advanced Separation Technologies (must pre-register at ASTEC’s booth/complimentary lunch provided)

    12:00-1:00pm VENDOR SEMINAR on Properties and Capabilities of the New DACH-DNB Chiral Stationary Phase/Chiral HPLC Method Development Question and Answer Session, sponsored by Regis Technologies (must pre-register at Regis’ booth/complimentary lunch provided)

    1:15-2:45pm POSTER SESSION in Exhibit Hall

    Session 4. Physical/Theoretical Aspects of Chirality (Parallel Session)

    3:00pm Redox-Induced Inversion of Ligand Helicity in Tripodal Copper Complexes—J.W. Canary, New York University, New York, NY, USA

    3:30pm The Ion-Pair Version of the Phenomenon of Racemization, Retention and Inversion—A.A. Gevorkyan, A.S. Arakelyan, K.A. Petrosyan, Armenian National Academy of Sciences, Yerevan, ARMENIA

    3:50pm Determination of Interconversion Energy Barriers by Separation Methods—J. Krupcik, Slovak University of Technology, Bratislava, SLOVAKIA

    4:10pm Break in Exhibit Hall

    4:40pm Exhibits Close

    4:40pm Molecular Modeling of Chiral Recognition by Cyclodextrins. Is it Reliable?—H. Dodziuk, O. Lukin, Polish Academy of Science, Warsaw, POLAND

    5:10pm Application of Microscopic Models of Chirality to Second Harmonic Reflection—M.C. Schanne-Klein1, H. Mesnil1, F. Hache1, M. Alexandre2, G. Lemercier2, C. Andraud2, 1CNRS/Ecole Polytechnique, Palaiseau, FRANCE; 2CNRS/ENS Lyon, Lyon, FRANCE

    5:30pm BIS(Zinc Porphyrin) as a Supramolecular Chirality Sensor: Rationalization and Applications of the Ligand Bulkiness Effect—V.V. Borovkov1, N. Yamamoto2, J.M. Lintuluoto1, T. Tanaka2, Y. Inoue1, 1Inoue Photochirogenesis Project, Osaka, JAPAN; 2Wako Pure Chemical Industries, Hyogo, JAPAN

    5:50pm Session Ends

    6:30pm BANQUET DINNER & DESSERT RECEPTION AT WALT DISNEY WORLD'S EPCOT®
    Travel with us from the Contemporary Resort in the Magic Kingdom to Walt Disney World's Epcot® where we will dine in the American Adventure Rotunda. After dinner, Regis Technologies will host a Dessert Reception beside the World Showcase Lagoon offering a spectacular view to enjoy Epcots® IllumiNations—a spectacular rhapsody of lasers, lights, fountains, music and fireworks! $50 per person includes bus, admission into Epcot®, dinner, dessert and show. Reserve early as seating is limited; see Meeting Registration Form.

    Session 5. Enantioselective Synthesis (Parallel Session)

    2:50pm Syntheses of Pyrone-Containing Natural Products—P.V. Ramachandran, M.V.R. Reddy, Purdue University, West Lafayette, IN, USA

    3:20pm Engineered Racemic Catalysis—K. Mikami, Tokyo Institute of Technology, Tokyo, JAPAN

    3:50pm Epoxidation of Olefins via Chiral Dioxiranes: Enhance Activity of Ketones Having an Axial Halogen and Higher Enantioselectivity Through Axial C-5 Substitution—A. Solladié-Cavallo, ECPM/Université Louis Pasteur, Strasbourg, FRANCE

    4:10pm Break in Exhibit Hall

    4:40pm Exhibits Close

    4:40pm Asymmetric Epoxidation of Olefins via Chiral Dioxiranes—Y. Shi, Colorado State University, Fort Collins, CO, USA

    5:10pm Reactions, Dynamics, and Structure of Chiral Organolithiums—R.E. Gawley, University of Miami, Coral Gables, FL, USA

    5:35pm Problems of the Vocabulary of Chirality: On the Usage of Enantiomer and Related Terms—J. Gal, University of Colorado School of Medicine, Denver, CO, USA

    5:55pm Session Ends

    6:30pm BANQUET DINNER & DESSERT RECEPTION AT WALT DISNEY WORLD'S EPCOT®
    Travel with us from the Contemporary Resort in the Magic Kingdom to Walt Disney World's Epcot® where we will dine in the American Adventure Rotunda. After dinner, Regis Technologies will host a Dessert Reception beside the World Showcase Lagoon offering a spectacular view to enjoy Epcots® IllumiNations—a spectacular rhapsody of lasers, lights, fountains, music and fireworks! $50 per person includes bus, admission into Epcot®, dinner, dessert and show. Reserve early as seating is limited; see Meeting Registration Form.

    Wednesday, July 18, 2001

    7:45-8:45am VENDOR SEMINAR on Chiral Separations by SFC, sponsored by Berger Instruments (must pre-register at Berger Instrument’s booth/complimentary continental breakfast provided)

    Session 6. Absolute Configuration / Chiroptical Spectroscopy (Parallel Session)

    9:00am Absolute Configuration and Enantiomeric Purity Determination Using Vibrational Circular Dichroism—P.L. Polavarapu, Vanderbilt University, Nashville, TN, USA

    9:30am Chirality-Dependent Interaction Between Molecular Propeller Structures in Solution. Chiral Recognition and Discrimination Processes Modulated by Temperature and Incremental Changes in Structural Chirality—J.P. Bolender, F.S. Richardson, University of San Diego, San Diego, CA, USA

    9:50am Comparison of Vibrational Circular Dichroism, Electronic Circular Dichroism and Optical Rotation for Enantiomeric Purity Determination of Mixtures of Chiral Pharmaceutical Molecules—L.A. Nafie1, X. Cao1, C. Guo1, T.B. Freedman1, R.K. Dukor2, R.D. Shah3, 1Syracuse University, Syracuse, NY, USA; 2BioTools, Elmhurst, IL, USA; 3R.W. Johnson Pharmaceutical Research Institute, Spring House, PA, USA

    10:10am Break

    10:40am Rhodopsin and Circular Dichroism—K. Nakanishi, D. Lichtblau, Columbia University, New York, NY, USA

    11:10am New Platinum(II) Complexes Containing Chiral Secondary Amines: Efficient and Versatile Chiral Derivatizing Agents for the Determination of the Enantiomeric Composition and Absolute Configuration of Chiral Unsaturated Compounds by 195Pt NMR Spectroscopy—G. Uccello-Barretta, University of Pisa, Pisa, ITALY

    11:30am High Precision Measurement of Enantiomeric Excess Using Laser Polarimetry—G.W. Yanik1, D.R. Bobbitt2, S. Linder2, 1PDR-Chiral, Palm Beach Gardens, FL, USA; 2University of Arkansas, Fayetteville, AR, USA

    11:50am Session Ends

    12:00-1:00pm VENDOR SEMINAR on Optimizing the Development and Production of Enantiomerically Pure Pharmaceuticals–Techniques and Systems Utilizing "Advanced Laser Polarimeter" Technology, sponsored by PDR-Chiral (must pre-register at PDR-Chiral’s booth/complimentary lunch provided)

    Session 7. Enantiomeric Separations II (Parallel Session)

    9:00am Bridging the Gulf Between Preferential Resolution and Diastereomeric Resolution—K. Saigo, University of Tokyo, Tokyo, JAPAN

    9:30am Practical Preparative, Commercial-Scale SMB Chromatography in a cGMP Environment—O. Dapremont, T.G. Archibald, G.G. McParland, A.A. Malik, Aerojet Fine Chemicals, Rancho Cordova, CA, USA

    9:50am Preparative Chiral Continuous Free-Flow Electrophoresis Using Sulfated Cyclodextrins—A.M. Stalcup, S.R. Gratz, E.G. Yanes, E. Scheiderman, University of Cincinnati, Cincinnati, OH, USA

    10:10am Break

    10:40am Polymeric Surfactants as New Reagents for Separating Chiral Compounds—I.M. Warner, Louisiana State University, Baton Rouge, LA, USA

    11:10am Synergistic Effects Using the Macrocyclic Antibiotics Ristocetin A and Vancomycin in Capillary Electrophoresis—T.J. Ward, Millsaps College, Jackson, MS, USA

    11:30am Enantiomeric Determination of Pantoprazol in Human Plasma by Multidimensional HPLC—Q.B. Cass1, A.L.G. Degani1, N.M. Cassiano1, J. Pedrazolli, Jr.2, 1Universidade Federal de São Carlos, BRAZIL; 2Unidade de Farmacologia Clinica, Bragança Paulista, BRAZIL

    11:50am Session Ends

    12:00-1:00pm VENDOR SEMINAR on Optimizing the Development and Production of Enantiomerically Pure Pharmaceuticals–Techniques and Systems Utilizing "Advanced Laser Polarimeter" Technology, sponsored by PDR-Chiral (must pre-register at PDR-Chiral’s booth/complimentary lunch provided)

    Session 8. Chirality in Pharmacology & Regulatory Affairs

    1:30pm Investigation of the Stereoselective In Vitro Biotransformation of Thalidomide Using a Dual Cyclodextrin System in Capillary Electrophoresis—G. Blaschke, M. Meyring, University of Muenster, Muenster, GERMANY

    2:00pm The Strategy of Chiral Switches of Blockbuster Drugs Undergoing Patents Expirations—I. Agranat, H. Caner, The Hebrew University of Jerusalem, Jerusalem, ISRAEL

    2:20pm Chiral LC/MS Method for the Enantioselective Differentiation of Metalaxyl From its Biologically Active R-Enantiomer, Mefenoxam, in Agricultural Commodities—M.C. Grunenwald, R.K. Williams, Syngenta Crop Protection, Greensboro, NC, USA

    2:40pm Break

    3:10pm Drugs of Abuse in Human Hair: Determination of the Enantiomeric Composition of Amphetamine and Methamphetamine in Hair by Liquid Chromatography—K.W. Phinney, L.C. Sander, National Institute of Standards and Technology, Gaithersburg, MD, USA

    3:30pm FDA Perspectives on Quality Control for Chiral Pharmaceuticals—S. P. Miller, U.S. Food & Drug Administration, Rockville, MD, USA

    4:05pmSpecial Discussion Session Dedicated to Regulatory Issues
    including NIST Chiral Standards and FDA Proposals (bring your questions, comments & opinions)

    4:25pm Invitation to Chirality 2002

    4:30pm Meeting Adjourns

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    POSTER PRESENTATIONS
    Session Times: 1:15 - 2:45 pm
    Abstracts for poster presentation will be accepted until June 15
    The size of each poster board is 4 feet high by 8 feet wide

    • Comparative Study on the Chiral Resolution of b -Blockers on Cellulose Tris (3,5-Dimethylphenylcarbamate) Phases in Normal and Reversed Phase Modes—H.Y. Aboul-Enein1, M.G. Schmid2, O. Gecse2, Z. Szabo2, F. Kilár3, G. Gübitz2, I. Ali, 1King Faisal Specialist Hospital and Research Centre, Riyadh, SAUDI ARABIA; 2Karl-Franzens University of Graz, Graz, AUSTRIA; 3University of Pécs, Pécs, HUNGARY
    • Comparative Study of the Enantiomeric Resolution of Racemic Econazole, Miconazole and Sulconazole by HPLC on Various Cellulose Chiral Stationary Phases in Normal Phase Mode—H.Y. Aboul-Enein, I. Ali, King Faisal Specialist Hospital and Research Centre, Riyadh, SAUDI ARABIA
    • Chemometrically Supported Optimization of Enantioselective Separation in Series of Adrenoceptors with Normal-Phase Ion-Interaction Planar Chromatography Systems—G. Bazylaka, A. Zabinskab, H.Y. Aboul-Eneinc, aMedical University of Lodz, Lodz, POLAND; bMaria Curie-Sklodowska University, Lublin, POLAND; cKing Faisal Specialist Hospital and Research Centre, Riyadh, SAUDI ARABIA
    • Chiral Recognition Probed by Steady-State Luminescence Measurements—J.P. Bolender, A. Meyers, J. Cordaro, R.S. Ries, University of San Diego, San Diego, CA, USA
    • Multidimensional Chromatography Applied to the Analysis of the Aldo-Keto Reductase-Mediated Reduction of Metyrapone in Plasma by Direct Injection—Q.B. Cass1, N.M. Cassiano1, A.L.G. Degani1, I. Wainer2, 1Universidade Federal de São Carlos, BRAZIL; 2Georgetown University, Washington, DC, USA
    • Enantiodifferentiation of Chiral 1,4-Disubstituted Piperazine and 3-Amino-2-Oxazolidinone Derivatives with Hypnotic-Sedative and Antidepressive Activities on Cellulose Based Stationary Phases—Z. Chilmonczyk1,2, H. Ksyciska3, M. Mazgajska3, J. Krzywda3, 1Drug Institute, Warsaw, POLAND; 2University of Biaystok, Biaystok, POLAND; 3Pharmaceutical Research Institute, Warsaw, POLAND
    • N-(o-Aryl)Rhodanine Diastereomers: Diastereoisomerism due to Hindered Rotation—I. Dogan, A. Yaman, Bogazici University, Istanbul, TURKEY
    • Chemometric Approaches to Enantioselective HPLC and SFC Method Development Using In-Line Polarimetric Detection—F. Geiser, W.L. Champion, Jr., K.B. Prickett, Chiral Technologies, Exton, PA, USA
    • The Ion Pair Version of the Optical Induction in Addition Reactions of Metal Chelated Complexes of Dehydroalanine and Related Compounds—A.A. Gevorkyan, A.S. Arakelyan, K.A. Petrosyan, Armenian National Academy of Sciences, Yerevan, ARMENIA
    • Transient Circular Dichroism Spectra Measured in a Femtosecond Pump-Probe Experiment—H. Mesnil, M.C. Schanne-Klein, F. Hache, M. Alexandre*, G. Lemercier*, C. Andraud*, CNRS/Ecole Polytechnique, Palaiseau, FRANCE; *CNRS/ENS Lyon, Lyon, FRANCE
    • Sympathomimetics Enantiomeric Purity Determinations by 1H NMR—G.M. Hanna, Food and Drug Administration, Jamaica, NY, USA
    • Preparation and Application of a New Ligand Exchange Chiral Stationary Phase—M.H. Hyun, S.C. Han, Pusan National University, Pusan, KOREA
    • Unique Chiral Ionic Interaction Mechanism on Macrocyclic

      • Glycopeptide CSPs in HPLC—J.T. Lee, T.E. Beesley, Advanced Separation
      Technologies, Whippany, NJ, USA
    • A Novel Amino Acid Surfactant for Separation of Chiral Compounds Using Micellar Capillary Electrophoresis—S. Mwongela, C. Akbay, I. Warner, Louisiana State University, Baton Rouge, LA, USA
    • Optical Resolution Ability as Chiral Stationary Phase Prepared from Poly(N—Methylbenzylmaleimide) for HPLC—T. Oishi, K. Onimura, H. Tsutsumi, Yamaguchi University, Yamaguchi, JAPAN
    • Asymmetric Anionic Polymerization of N-Arylmaleimide Bearing Azo Groups and Their Optical Resolution Ability as Chiral Stationary Phase for HPLC—K. Onimura, I. Yukio, H. Tsutsumi, T. Oishi, Yamaguchi University, Yamaguchi, JAPAN
    • Standard Reference Materials for the Evaluation of Chiral Stationary Phase Performance in Liquid and Supercritical Fluid Chromatography—K.W. Phinney, L.C. Sander, National Institute of Standards and Technology, Gaithersburg, MD, USA
    • Use of Tartaric Acid in Capillary Electrophoresis—T.L. Blackmon Robinson, C. Akbay, I. Warner, Louisiana State University, Baton Rouge, LA, USA
    • Enantioselective Chromatography Using On-Line Chiroptical Detections: Mobile-Phase Optimization—R. Shah1, F. Geiser2, M. Shaimi2, 1R.W. Johnson Pharmaceutical Research Institute, Spring House, PA, USA; 2Chiral Technologies, Exton, PA, USA
    • Large Scale Applications of Preparative Chromatography—G. Pigorini, NovaSep SAS, Vandoeuvre-les-Nancy, FRANCE
    • N-Methyl Barbiturates: Stereospecific Actions of Chiral Isomers—F. Torrens, Universitat de València, Burjassot (València), SPAIN
    • On-Line Simultaneous Determination of S and R Perindopril Using Amperometric Biosensors as Detectors in Flow Systems—J.F. van Staden1, R.-I. Stefan1, L.V. Mulaudzi1, H.Y. Aboul-Enein2, 1University of Pretoria, Pretoria, SOUTH AFRICA; 2King Faisal Specialist Hospital and Research Centre, Riyadh, SAUDI ARABIA
    • Method Development of Chiral Separations on LC-MS—T.E. Beesley, Advanced Separation Technologies, Whippany, NJ, USA
    • Synthesis and Absolute Stereochemistry of Chiral Doubly Added Fullerenes— K. Yoshida, S. Osawa, K. Monde, M. Watanabe, N. Harada, Tohoku University, Sendai, JAPAN
    • Preparation of New Types of Juvenogens: Reaction Modeling—M. Zarevúcka, D. Šaman, Z. Wimmer, Academy of Sciences of the Czech Republic, Prague, CZECH REPUBLIC
    • Enzyme-Mediated Enrichment of Polyunsaturated Fatty Acids and Their Esters From Blackcurrant Oil—M. Vaceka, M. Zarevúckab, Z. Wimmer b, K. Stránskýb, K. Demnerováa, M.-D. Legoyc, 1Institute of Chemical Technology, Prague, CZECH REPUBLIC; bInstitute of Organic Chemistry and Biochemistry, Prague, CZECH REPUBLIC; cUniversité de La Rochelle, La Rochelle, FRANCE
    • The Effect of Cyclodextrin in Chiral Recognition Using Various Spectroscopic Techniques—B. Cedillo1, R. Agbaria2, I.M. Warner1, Louisiana State University, Baton Rouge, LA, USA; 2Lawrence Livermore National Laboratory, Livermore, CA, USA
    • Effect of 1-Hexanol and Cyclohexanol Concentration on Resolution Ability of Polymeric Surfactant for Chiral Analytes—J. Tarus, I.M. Warner, Louisiana State University, Baton Rouge, LA, USA
    • Determination of Absolute Configuration in Chiral Pharmaceutical Molecules Using Vibrational Circular Dichroism Spectroscopy—L.A. Nafie1, T.B. Freedman1, R.K. Dukor2, E.R. Kellenbach3, P.J.C.M. Hoof4, 1Syracuse University, Syracuse, NY, USA; 2BioTools, Elmhurst, IL, USA; 3Organon, Riom, FRANCE; 4Organon, Oss, THE NETHERLANDS
    • Utility of CD (Circular Dichroism) Chiral Detection in Amino Acid and Protein Analysis by HPLC—K. Kudo1, K. Iwaya1, M. Bounoshita1, M. Saito2, 1Jasco, Tokyo, JAPAN; 2Jasco, Easton, MD, USA
    • Preparation of New Brush-Type Chiral Stationary Phases with Improved Properties—V. Vinkovica, D. Kontreca, L. Navarinib, A. Acedc, V. Sunjica, aRuder Boskovic Institute, Zagreb, CROATIA; bPOLYtech, Trieste, ITALY; cIris Technologies, Lawrence, KS, USA
    • Use of CGL, HPLC, and Couplage GLC-MS for Analysis and Enantioseparation of Lipdic Compounds—H. Kallel, Campus Universitaire, Tunis, TUNISIA
    • Fully Automated Chiral Method Development Stations for HPLC and SFC— G.W. Yanik, PDR-Chiral, Palm Beach Gardens, FL, USA
    • Rational Design of Helical Polymers and Their Use as Asymmetric Catalysts— T. Takata, Y. Furusho, N. Makino, T. Takeuchi, Osaka Prefecture University, Osaka, JAPAN
    • Circular Dichroism in the VUV Photofragmentation Mass Spectra of (S)-(+)-2-Amino-1-Butanol—R.A. Mackie, R. Browning, C.J. Latimer, S.W.J. Scully, K.F. Dunn, The Queen’s University of Belfast, Belfast, IRELAND
    • Experimental and Theoretical Study of Diastereomeric Solvates of Chiral Hydroxyfuranones and Pirkle’s Alcohols—C. García-Martíneza, F. Méndez-Ruizb, aUniversidad Autónoma Metropolitana-Azcapotzalco, Col. Reynosa Tamaulipas, MEXICO; Universidad Autónoma Metropolitana-Iztapalapa, MEXICO
    • New Examples of Asymmetric Catalysis Using Metal Complexes of Chiral Hydrophosphoranes—K.N. Gavrilova, A.I. Polosukhinb, O.G. Bondarevb, S.E. Lyubimova, P.A. Evansc, V.A. Davankovb, aRyazan State Pedagogic University, Ryazan, RUSSIA; bRussian Academy of Sciences, Moscow, RUSSIA; cUniversity of Delaware, Newark, DE, USA
    • Capillary Electrophoresis and Solid Phase Extraction Studies on Enantiomers of Vesamicol in Serum Samples Using Cyclodextrin Additives—M. Zhou, J.T. Stewart, The University of Georgia, Athens, GA, USA
    • Synthesis and Helicity Induction of Stereoregular Polyacetylenes Bearing a Carboxy Group with Natural Amino Acids in Water—H. Goto, H. Onouchi, A.M. Saito, K. Maeda, E. Yashima, Nagoya University, Nagoya, JAPAN
    • Separation of Peaks from Complex Sample Matrices for More Efficient Chiral Separations—C. Henry, M. Vaughn, S. Cole, GlaxoSmithKline, Research Triangle Park, NC, USA
    • Absolute Configuration and Enantiomeric Excess Determination by Exciton-Coupled Circular Dichroism Studies of CU(II) Complexes of N,N-BIS(2-Quinolylmethyl) Amino Acids and Amino Alcohols—A.E. Holmes, S. Zahn, J.W. Canary, New York University, New York, NY, USA
    • Successful Resolution of DL-Tartaric Acid via Crystallization of Diastereomeric Salts Formation: Simultaneous Optimization of Optical Purity and Yield of the Resolved Diastereomeric Salts by Response Surface Modeling in Central Composite Design—L. Kokila, S. Cai, C. Kongchang, East China University of Science & Technology, Shanghai, PR CHINA
    • Efficient Immobilization of Polysaccharide Derivatives onto Silica Gel via Copolymerization with Vinyl Monomers and Evaluation of Their Chiral Recognition Ability—T. Kubota, T. Kusano, C. Yamamoto, E. Yashima, Y. Okamoto, Nagoya University, Nagoya, JAPAN
    • Chiralselect™—A High Throughput Screening Technology for Enantiomer Separation—J.L. Lin, S. McIlvain, W. Li, V. Sreenivasarao, Y. Zhou, E. Kirchhoff, D. Zembower, MediChem Research, Lemont, IL, USA
    • Enantioseparation on New and Easy-to-Prepare Continuous Beds for Capillary Electrochromatography—M.G. Schmid1, O. Lecnik1, N. Grobuschek1, G. Gübitz1, Á. Végvári2, S. Hjertén2, 1Karl-Franzens-University, Graz, AUSTRIA; 2Uppsala University, Uppsala, SWEDEN
    • Enantioseparation by Using Chitin Carbamate Derivatives as Chiral Stationary Phases—C. Yamamoto, T. Hayashi, Y. Okamoto, S. Kobayashi1, Nagoya University, Nagoya, JAPAN; 1Kyoto University, Kyoto, JAPAN
    • Helix-Helix Transition of an Optically Active Poly(Phenylacetylene) Derivative Bearing a Cyclodextrin Residue—E. Yashima1,2, K. Maeda1, O. Sato1, M. Watanabe1, 1Nagoya University, Nagoya, JAPAN; 1PRESTO, JST
    • Stereoselectivity in Competitive Peptide Synthesis—T. Miyazawaa, T. Hamadaa, A. Ozawaa, T. Munegumib, aKonan University, Kobe, JAPAN; bOyama National College of Technology, Oyama, JAPAN
    • A Comparison of Chiral Resolution of Econazole, Miconazole and Sulconazole by HPLC Using Normal Phase Amylose CSPS—H.Y. Aboul-Enein, I. Ali, King Faisal Specialist Hospital and Research Center, Riyadh, SAUDI ARABIA
    • Chirality and the Origin of Life: In Situ Enantiomeric Separation for Future Space Missions—C. Rodier1, D. Coscia1, R. Sternberg1, F. Raulin1, C. Vidal-Madjar2, 1LISA, Universités Paris VII et XII, Créteil, FRANCE; 2Université Paris XII, Thiais, FRANCE
    • Application of Solid-State Multinuclear CPMAS (13C, 29SI, 119SN) and CRAMPS (1H and 19F) of Transition Metal Complexes Supported on Modified Natural Chiral Polymers. New Approach for the Investigation of Chiral Complexes and Their Enantiomeric Mixtures—Y. Oprunenko, D. Mityuk, University of Moscow, Moscow, RUSSIA
    • Regio- and Stereoselective Hydroxylation of Taxoids by the Filamentous Fungus—S. Hu, D.-A. Sun, X. Tian, Q. Fang, Chinese Academy of Medical Sciences and Perking Union Medical College, Beijing, CHINA
    • Micellar Electrokinetic Capillary Chromatography Determination of S (+) and R (-) Arotinolol in Serum Using UV Detection and Solid Phase Extraction—M.M. Hefnawy, University of Mansoura, Mansoura, EGYPT
    • High Resolution CE Enantioseparation of Neutral Chiral Sulfoxides—Y. Liu, M. Rodriguez, L. He, W. Jenks, D.W. Armstrong, Iowa State University, Ames, IA, USA
    • Laser Polarimetry Detection to Monitor and Quantitate Microbes in Commercial Products and Fermentation Processes—B. Zhang, D.W. Armstrong, Iowa State University, Ames, IA, USA
    • Enantiomeric Separations of Chiral Sulfoxides Using Macrocyclic Glycopeptide (Chirobiotic) Chiral Stationary Phases—L. Xiao, W. Jenks, D.W. Armstrong, Iowa State University, Ames, IA, USA
    • Use of Cyclodextrins and Derivatized Cyclodextrin Chiral Stationary Phases for the Enantioseparation of Aromatic and Aliphatic Sulfoxides—C. Mitchell, M. Desai, W. Jenks, D.W. Armstrong, Iowa State University, Ames, IA, USA
    • Rapid, High Efficiency SFC Separation of Enantiomers on Chirobiotic Stationary Phases—M. Rodriguez, Y. Liu, L. He, B. Zhang, L. Xiao, C. Mitchell, M. Desai, J. Anderson, J. Ding, W. Jenks, D.W. Armstrong, Iowa State University, Ames, IA, USA
    • Reversal of Enantiomeric Elution Order on Macrocyclic Glycopeptide (Chirobiotic) CSPs—B. Zhang, L. Xiao, J.T. Lee, F. Hui, D.W. Armstrong, Iowa State University, Ames, IA, USA
    • Study on the Enantioresolution of Native Amino Acids and Derivatized Amino Acids on Macrocyclic Antibiotics—I.A. Ananieva1, V.A. Davankov2, D.W. Armstrong3, 1Moscow State University, Moscow, RUSSIA; 2Russia Academy of Sciences, Moscow, RUSSIA; 3Iowa State University, Ames, IA, USA
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